Acute Multiple Organ Failure in Adult Mice Deleted for the Developmental Regulator Wt1

There is much interest in the mechanisms that regulate adult tissue homeostasis and their relationship to processes governing foetal development. Mice deleted for the Wilms' tumour gene, Wt1, lack kidneys, gonads, and spleen and die at mid-gestation due to defective coronary vasculature. Wt1 is...

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Bibliographic Details
Main Authors: Chau, You-Ying, Brownstein, David, Mjoseng, Heidi, Lee, Wen-Chin, Buza-Vidas, Natalija, Nerlov, Claus, Jacobsen, Sten Eirik, Perry, Paul, Berry, Rachel, Thornburn, Anna, Sexton, David, Morton, Nik, Hohenstein, Peter, Freyer, Elisabeth, Samuel, Kay, van't Hof, Rob, Hastie, Nicholas
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245305/