VectorBase: improvements to a bioinformatics resource for invertebrate vector genomics

VectorBase (http://www.vectorbase.org) is a NIAID-supported bioinformatics resource for invertebrate vectors of human pathogens. It hosts data for nine genomes: mosquitoes (three Anopheles gambiae genomes, Aedes aegypti and Culex quinquefasciatus), tick (Ixodes scapularis), body louse (Pediculus hum...

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Main Authors: Megy, Karine, Emrich, Scott J., Lawson, Daniel, Campbell, David, Dialynas, Emmanuel, Hughes, Daniel S.T., Koscielny, Gautier, Louis, Christos, MacCallum, Robert M., Redmond, Seth N., Sheehan, Andrew, Topalis, Pantelis, Wilson, Derek
Format: Online
Language:English
Published: Oxford University Press 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245112/
id pubmed-3245112
recordtype oai_dc
spelling pubmed-32451122012-01-10 VectorBase: improvements to a bioinformatics resource for invertebrate vector genomics Megy, Karine Emrich, Scott J. Lawson, Daniel Campbell, David Dialynas, Emmanuel Hughes, Daniel S.T. Koscielny, Gautier Louis, Christos MacCallum, Robert M. Redmond, Seth N. Sheehan, Andrew Topalis, Pantelis Wilson, Derek Articles VectorBase (http://www.vectorbase.org) is a NIAID-supported bioinformatics resource for invertebrate vectors of human pathogens. It hosts data for nine genomes: mosquitoes (three Anopheles gambiae genomes, Aedes aegypti and Culex quinquefasciatus), tick (Ixodes scapularis), body louse (Pediculus humanus), kissing bug (Rhodnius prolixus) and tsetse fly (Glossina morsitans). Hosted data range from genomic features and expression data to population genetics and ontologies. We describe improvements and integration of new data that expand our taxonomic coverage. Releases are bi-monthly and include the delivery of preliminary data for emerging genomes. Frequent updates of the genome browser provide VectorBase users with increasing options for visualizing their own high-throughput data. One major development is a new population biology resource for storing genomic variations, insecticide resistance data and their associated metadata. It takes advantage of improved ontologies and controlled vocabularies. Combined, these new features ensure timely release of multiple types of data in the public domain while helping overcome the bottlenecks of bioinformatics and annotation by engaging with our user community. Oxford University Press 2012-01 2011-11-30 /pmc/articles/PMC3245112/ /pubmed/22135296 http://dx.doi.org/10.1093/nar/gkr1089 Text en Published by Oxford University Press 2011. http://creativecommons.org/licenses/by-nc/3.0 This is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License (http://creativecommons.org/licenses/by-nc/3.0), which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Megy, Karine
Emrich, Scott J.
Lawson, Daniel
Campbell, David
Dialynas, Emmanuel
Hughes, Daniel S.T.
Koscielny, Gautier
Louis, Christos
MacCallum, Robert M.
Redmond, Seth N.
Sheehan, Andrew
Topalis, Pantelis
Wilson, Derek
spellingShingle Megy, Karine
Emrich, Scott J.
Lawson, Daniel
Campbell, David
Dialynas, Emmanuel
Hughes, Daniel S.T.
Koscielny, Gautier
Louis, Christos
MacCallum, Robert M.
Redmond, Seth N.
Sheehan, Andrew
Topalis, Pantelis
Wilson, Derek
VectorBase: improvements to a bioinformatics resource for invertebrate vector genomics
author_facet Megy, Karine
Emrich, Scott J.
Lawson, Daniel
Campbell, David
Dialynas, Emmanuel
Hughes, Daniel S.T.
Koscielny, Gautier
Louis, Christos
MacCallum, Robert M.
Redmond, Seth N.
Sheehan, Andrew
Topalis, Pantelis
Wilson, Derek
author_sort Megy, Karine
title VectorBase: improvements to a bioinformatics resource for invertebrate vector genomics
title_short VectorBase: improvements to a bioinformatics resource for invertebrate vector genomics
title_full VectorBase: improvements to a bioinformatics resource for invertebrate vector genomics
title_fullStr VectorBase: improvements to a bioinformatics resource for invertebrate vector genomics
title_full_unstemmed VectorBase: improvements to a bioinformatics resource for invertebrate vector genomics
title_sort vectorbase: improvements to a bioinformatics resource for invertebrate vector genomics
description VectorBase (http://www.vectorbase.org) is a NIAID-supported bioinformatics resource for invertebrate vectors of human pathogens. It hosts data for nine genomes: mosquitoes (three Anopheles gambiae genomes, Aedes aegypti and Culex quinquefasciatus), tick (Ixodes scapularis), body louse (Pediculus humanus), kissing bug (Rhodnius prolixus) and tsetse fly (Glossina morsitans). Hosted data range from genomic features and expression data to population genetics and ontologies. We describe improvements and integration of new data that expand our taxonomic coverage. Releases are bi-monthly and include the delivery of preliminary data for emerging genomes. Frequent updates of the genome browser provide VectorBase users with increasing options for visualizing their own high-throughput data. One major development is a new population biology resource for storing genomic variations, insecticide resistance data and their associated metadata. It takes advantage of improved ontologies and controlled vocabularies. Combined, these new features ensure timely release of multiple types of data in the public domain while helping overcome the bottlenecks of bioinformatics and annotation by engaging with our user community.
publisher Oxford University Press
publishDate 2012
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3245112/
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