Unusually Strong Temperature Dependence of P2X3 Receptor Traffic to the Plasma Membrane
ATP-gated P2X3 receptors are expressed by nociceptive neurons and participate in transduction of pain. Responsiveness of P2X3 receptors is strongly reduced at low temperatures, suggesting a role for these receptors in analgesic effects of cooling. Since sustained responsiveness depends on receptor t...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Frontiers Research Foundation
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3243083/ |