A resource of vectors and ES cells for targeted deletion of microRNAs in mice
The 21-23 nucleotide single-stranded RNAs classified as microRNAs (miRNA) perform fundamental roles in a wide range of cellular and developmental processes. miRNAs regulate protein expression through sequence-specific base pairing with target messenger RNAs (mRNA) reducing both their stability and t...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3242032/ |