Cdc14b regulates mammalian RNA polymerase II and represses cell cycle transcription

Cdc14b regulates mammalian RNA polymerase II and represses cell cycle transcription

Cdc14 is an essential phosphatase in yeast but its role in the mammalian cell cycle remains obscure. We report here that Cdc14b-knockout cells display unscheduled induction of multiple cell cycle regulators resulting in early entry into DNA replication and mitosis from quiescence. Cdc14b dephosphory...

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Bibliographic Details
Main Authors: Guillamot, María, Manchado, Eusebio, Chiesa, Massimo, Gómez-López, Gonzalo, Pisano, David G., Sacristán, María P., Malumbres, Marcos
Format: Online
Language:English
Published: Nature Publishing Group 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240995/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240995/

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