Structural insights into the molecular ruler mechanism of the endoplasmic reticulum aminopeptidase ERAP1
Endoplasmic reticulum aminopeptidase 1 (ERAP1) is an essential component of the immune system, because it trims peptide precursors and generates the N--restricted epitopes. To examine ERAP1's unique properties of length- and sequence-dependent processing of antigen precursors, we report a 2.3 Å...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
Nature Publishing Group
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240994/ |