Visualization of plasmid delivery to keratinocytes in mouse and human epidermis

The accessibility of skin makes it an ideal target organ for nucleic acid-based therapeutics; however, effective patient-friendly delivery remains a major obstacle to clinical utility. A variety of limited and inefficient methods of delivering nucleic acids to keratinocytes have been demonstrated; f...

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Bibliographic Details
Main Authors: González-González, Emilio, Kim, Yeu-Chun, Speaker, Tycho J., Hickerson, Robyn P., Spitler, Ryan, Birchall, James C., Lara, Maria Fernanda, Hu, Rong-hua, Liang, Yanhua, Kirkiles-Smith, Nancy, Prausnitz, Mark R., Milstone, Leonard M., Contag, Christopher H., Kaspar, Roger L.
Format: Online
Language:English
Published: Nature Publishing Group 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240989/