Drosophila Ribosomal Protein Mutants Control Tissue Growth Non-Autonomously via Effects on the Prothoracic Gland and Ecdysone

Drosophila Ribosomal Protein Mutants Control Tissue Growth Non-Autonomously via Effects on the Prothoracic Gland and Ecdysone

The ribosome is critical for all aspects of cell growth due to its essential role in protein synthesis. Paradoxically, many Ribosomal proteins (Rps) act as tumour suppressors in Drosophila and vertebrates. To examine how reductions in Rps could lead to tissue overgrowth, we took advantage of the obs...

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Bibliographic Details
Main Authors: Lin, Jane I., Mitchell, Naomi C., Kalcina, Marina, Tchoubrieva, Elly, Stewart, Mary J., Marygold, Steven J., Walker, Cherryl D., Thomas, George, Leevers, Sally J., Pearson, Richard B., Quinn, Leonie M., Hannan, Ross D.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240600/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3240600/

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