N-(2-Fluorophenyl)-5-[(4-methoxyphenyl)aminomethyl]-6-methyl-2-phenylpyrimidin-4-amine
The conformation of the title molecule, C25H23FN4O, is mainly determined by an intramolecular N—H⋯N hydrogen bond closing a six-membered ring and the dihedral angles between the pyrimidine ring and the three benzene rings which are 12.8 (2), 12.0 (2) and 86.1 (2)°. An intramolecular N—H⋯F intera...
| Main Authors: | , , , |
|---|---|
| Format: | Online |
| Language: | English |
| Published: |
International Union of Crystallography
2011
|
| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238833/ |
| id |
pubmed-3238833 |
|---|---|
| recordtype |
oai_dc |
| spelling |
pubmed-32388332011-12-23 N-(2-Fluorophenyl)-5-[(4-methoxyphenyl)aminomethyl]-6-methyl-2-phenylpyrimidin-4-amine Cieplik, Jerzy Pluta, Janusz Bryndal, Iwona Lis, Tadeusz Organic Papers The conformation of the title molecule, C25H23FN4O, is mainly determined by an intramolecular N—H⋯N hydrogen bond closing a six-membered ring and the dihedral angles between the pyrimidine ring and the three benzene rings which are 12.8 (2), 12.0 (2) and 86.1 (2)°. An intramolecular N—H⋯F interaction also occurs. The crystal stucture is stabilized by weak C—H⋯O and C—H⋯π interactions. An intermolecular N—H⋯N interaction is also observed. International Union of Crystallography 2011-11-05 /pmc/articles/PMC3238833/ /pubmed/22199686 http://dx.doi.org/10.1107/S1600536811045028 Text en © Cieplik et al. 2011 http://creativecommons.org/licenses/by/2.0/uk/ This is an open-access article distributed under the terms of the Creative Commons Attribution Licence, which permits unrestricted use, distribution, and reproduction in any medium, provided the original authors and source are cited. |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Cieplik, Jerzy Pluta, Janusz Bryndal, Iwona Lis, Tadeusz |
| spellingShingle |
Cieplik, Jerzy Pluta, Janusz Bryndal, Iwona Lis, Tadeusz N-(2-Fluorophenyl)-5-[(4-methoxyphenyl)aminomethyl]-6-methyl-2-phenylpyrimidin-4-amine |
| author_facet |
Cieplik, Jerzy Pluta, Janusz Bryndal, Iwona Lis, Tadeusz |
| author_sort |
Cieplik, Jerzy |
| title |
N-(2-Fluorophenyl)-5-[(4-methoxyphenyl)aminomethyl]-6-methyl-2-phenylpyrimidin-4-amine |
| title_short |
N-(2-Fluorophenyl)-5-[(4-methoxyphenyl)aminomethyl]-6-methyl-2-phenylpyrimidin-4-amine |
| title_full |
N-(2-Fluorophenyl)-5-[(4-methoxyphenyl)aminomethyl]-6-methyl-2-phenylpyrimidin-4-amine |
| title_fullStr |
N-(2-Fluorophenyl)-5-[(4-methoxyphenyl)aminomethyl]-6-methyl-2-phenylpyrimidin-4-amine |
| title_full_unstemmed |
N-(2-Fluorophenyl)-5-[(4-methoxyphenyl)aminomethyl]-6-methyl-2-phenylpyrimidin-4-amine |
| title_sort |
n-(2-fluorophenyl)-5-[(4-methoxyphenyl)aminomethyl]-6-methyl-2-phenylpyrimidin-4-amine |
| description |
The conformation of the title molecule, C25H23FN4O, is mainly determined by an intramolecular N—H⋯N hydrogen bond closing a six-membered ring and the dihedral angles between the pyrimidine ring and the three benzene rings which are 12.8 (2), 12.0 (2) and 86.1 (2)°. An intramolecular N—H⋯F interaction also occurs. The crystal stucture is stabilized by weak C—H⋯O and C—H⋯π interactions. An intermolecular N—H⋯N interaction is also observed. |
| publisher |
International Union of Crystallography |
| publishDate |
2011 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238833/ |
| _version_ |
1611494358952968192 |