Host Susceptibility to Brucella abortus Infection Is More Pronounced in IFN-γ knockout than IL-12/β2-Microglobulin Double-Deficient Mice

Host Susceptibility to Brucella abortus Infection Is More Pronounced in IFN-γ knockout than IL-12/β2-Microglobulin Double-Deficient Mice

Brucella abortus is a facultative intracellular bacterial pathogen that causes abortion in domestic animals and undulant fever in humans. IFN-γ, IL-12, and CD8+ T lymphocytes are important components of host immune responses against B. abortus. Herein, IFN-γ and IL-12/β2-microglobulin (β2-m) knocko...

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Bibliographic Details
Main Authors: Brandão, Ana Paula M. S., Oliveira, Fernanda S., Carvalho, Natalia B., Vieira, Leda Q., Azevedo, Vasco, Macedo, Gilson C., Oliveira, Sergio C.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238360/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238360/

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