Immunopathogenesis of primary biliary cirrhosis: an old wives' tale

Primary biliary cirrhosis (PBC) is a cholestatic liver disease characterised by the autoimmune destruction of the small intrahepatic bile ducts. The disease has an unpredictable clinical course, but may progress to fibrosis and cirrhosis. Although medical treatment with urseodeoxycholic acid is larg...

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Bibliographic Details
Main Authors: Smyk, Daniel S, Rigopoulou, Eirini I, Lleo, Ana, Abeles, Robin D, Mavropoulos, Athanasios, Billinis, Charalambos, Invernizzi, Pietro, Bogdanos, Dimitrios P
Format: Online
Language:English
Published: BioMed Central 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3238302/