Sequestration of phosphoinositides by mutated MARCKS effector domain inhibits stimulated Ca2+ mobilization and degranulation in mast cells
A new strategy for interfering with phosphoinositide-dependent processes at the plasma membrane uses high-avidity association of the polybasic MARCKS effector domain with negatively charged phospholipids to provide new insights into roles for phosphoinositides in IgE receptor signaling leading to ex...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
The American Society for Cell Biology
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3237632/ |