Current Status of the Immunomodulation and Immunomediated Therapeutic Strategies for Multiple Sclerosis

Multiple sclerosis (MS) is an autoimmune disease of the central nervous system, and CD4+ T cells form the core immunopathogenic cascade leading to chronic inflammation. Traditionally, Th1 cells (interferon-γ-producing CD4+ T cells) driven by interleukin 12 (IL12) were considered to be the encephalit...

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Bibliographic Details
Main Authors: Chen, Shyi-Jou, Wang, Yen-Ling, Fan, Hueng-Chuen, Lo, Wen-Tsung, Wang, Chih-Chien, Sytwu, Huey-Kang
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235500/