Betaine Treatment Attenuates Chronic Ethanol-Induced Hepatic Steatosis and Alterations to the Mitochondrial Respiratory Chain Proteome

Introduction. Mitochondrial damage and disruption in oxidative phosphorylation contributes to the pathogenesis of alcoholic liver injury. Herein, we tested the hypothesis that the hepatoprotective actions of betaine against alcoholic liver injury occur at the level of the mitochondrial proteome. Me...

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Bibliographic Details
Main Authors: Kharbanda, Kusum K., Todero, Sandra L., King, Adrienne L., Osna, Natalia A., McVicker, Benita L., Tuma, Dean J., Wisecarver, James L., Bailey, Shannon M.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235488/