The Association of Hypertension with Obesity and Metabolic Abnormalities among Chinese Children

The Association of Hypertension with Obesity and Metabolic Abnormalities among Chinese Children

A total of 8898 Chinese children (4580 boys and 4318 girls) aged 7–13 years in 6 cities of east China were recruited. Data on height, weight, waist circumference, blood pressure, serum lipid profiles, glucose, and insulin were collected. The overall prevalence of hypertension was 11.1%. Overweight a...

Full description

Bibliographic Details
Main Authors: Xu, Haiquan, Hu, Xiaoqi, Zhang, Qian, Du, Songming, Fang, Hongyun, Li, Ying, Ma, Jun, Li, Tingyu, Du, Lin, Guo, Hongwei, Xu, Guifa, Liu, Ailing
Format: Online
Language:English
Published: SAGE-Hindawi Access to Research 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235486/
id pubmed-3235486
recordtype oai_dc
spelling pubmed-32354862011-12-20 The Association of Hypertension with Obesity and Metabolic Abnormalities among Chinese Children Xu, Haiquan Hu, Xiaoqi Zhang, Qian Du, Songming Fang, Hongyun Li, Ying Ma, Jun Li, Tingyu Du, Lin Guo, Hongwei Xu, Guifa Liu, Ailing Research Article A total of 8898 Chinese children (4580 boys and 4318 girls) aged 7–13 years in 6 cities of east China were recruited. Data on height, weight, waist circumference, blood pressure, serum lipid profiles, glucose, and insulin were collected. The overall prevalence of hypertension was 11.1%. Overweight and obese children had a higher risk of developing hypertension than their counterparts (29.1%, 17.4%, and 7.8%, resp.) (P = 0.0001). The means levels of triglycerides, glucose, insulin, and HOMA-IR (1.0 mmol/L, 4.5 mmol/L, 8.4 mU/mL and 1.7, resp.) among hypertensive children were all significantly higher than their normotensive counterparts (0.8 mmol/L, 4.5 mmol/L, 5.9 mU/mL, and 1.2, resp.) (P = 0.0001). Compared with the healthy children, the risk (odds ratio, OR) of having hypertension among children with high triglycerides, hyperglycemia, and metabolic syndrome was 1.4 (95% confidence interval (CI): 1.0–2.0, P = 0.0334), 1.5 (95% CI: 0.9–2.5, P = 0.0890), and 2.8 (95%CI: 1.5–5.4, P = 0.0014), respectively, after controlling for age, gender, BMI, income level, parents' education level and puberty. In conclusion, overweight and obese children have higher risk of having hypertension and children with dyslipidemia, hyperglycemia, and metabolic syndrome and higher HOMA-IR have higher risk of developing hypertension. SAGE-Hindawi Access to Research 2011 2011-12-01 /pmc/articles/PMC3235486/ /pubmed/22187624 http://dx.doi.org/10.4061/2011/987159 Text en Copyright © 2011 Haiquan Xu et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Xu, Haiquan
Hu, Xiaoqi
Zhang, Qian
Du, Songming
Fang, Hongyun
Li, Ying
Ma, Jun
Li, Tingyu
Du, Lin
Guo, Hongwei
Xu, Guifa
Liu, Ailing
spellingShingle Xu, Haiquan
Hu, Xiaoqi
Zhang, Qian
Du, Songming
Fang, Hongyun
Li, Ying
Ma, Jun
Li, Tingyu
Du, Lin
Guo, Hongwei
Xu, Guifa
Liu, Ailing
The Association of Hypertension with Obesity and Metabolic Abnormalities among Chinese Children
author_facet Xu, Haiquan
Hu, Xiaoqi
Zhang, Qian
Du, Songming
Fang, Hongyun
Li, Ying
Ma, Jun
Li, Tingyu
Du, Lin
Guo, Hongwei
Xu, Guifa
Liu, Ailing
author_sort Xu, Haiquan
title The Association of Hypertension with Obesity and Metabolic Abnormalities among Chinese Children
title_short The Association of Hypertension with Obesity and Metabolic Abnormalities among Chinese Children
title_full The Association of Hypertension with Obesity and Metabolic Abnormalities among Chinese Children
title_fullStr The Association of Hypertension with Obesity and Metabolic Abnormalities among Chinese Children
title_full_unstemmed The Association of Hypertension with Obesity and Metabolic Abnormalities among Chinese Children
title_sort association of hypertension with obesity and metabolic abnormalities among chinese children
description A total of 8898 Chinese children (4580 boys and 4318 girls) aged 7–13 years in 6 cities of east China were recruited. Data on height, weight, waist circumference, blood pressure, serum lipid profiles, glucose, and insulin were collected. The overall prevalence of hypertension was 11.1%. Overweight and obese children had a higher risk of developing hypertension than their counterparts (29.1%, 17.4%, and 7.8%, resp.) (P = 0.0001). The means levels of triglycerides, glucose, insulin, and HOMA-IR (1.0 mmol/L, 4.5 mmol/L, 8.4 mU/mL and 1.7, resp.) among hypertensive children were all significantly higher than their normotensive counterparts (0.8 mmol/L, 4.5 mmol/L, 5.9 mU/mL, and 1.2, resp.) (P = 0.0001). Compared with the healthy children, the risk (odds ratio, OR) of having hypertension among children with high triglycerides, hyperglycemia, and metabolic syndrome was 1.4 (95% confidence interval (CI): 1.0–2.0, P = 0.0334), 1.5 (95% CI: 0.9–2.5, P = 0.0890), and 2.8 (95%CI: 1.5–5.4, P = 0.0014), respectively, after controlling for age, gender, BMI, income level, parents' education level and puberty. In conclusion, overweight and obese children have higher risk of having hypertension and children with dyslipidemia, hyperglycemia, and metabolic syndrome and higher HOMA-IR have higher risk of developing hypertension.
publisher SAGE-Hindawi Access to Research
publishDate 2011
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3235486/
_version_ 1611493173692989440

Similar Items