Age-Related Neuronal Degeneration: Complementary Roles of Nucleotide Excision Repair and Transcription-Coupled Repair in Preventing Neuropathology

Age-Related Neuronal Degeneration: Complementary Roles of Nucleotide Excision Repair and Transcription-Coupled Repair in Preventing Neuropathology

Neuronal degeneration is a hallmark of many DNA repair syndromes. Yet, how DNA damage causes neuronal degeneration and whether defects in different repair systems affect the brain differently is largely unknown. Here, we performed a systematic detailed analysis of neurodegenerative changes in mouse...

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Bibliographic Details
Main Authors: Jaarsma, Dick, van der Pluijm, Ingrid, de Waard, Monique C., Haasdijk, Elize D., Brandt, Renata, Vermeij, Marcel, Rijksen, Yvonne, Maas, Alex, van Steeg, Harry, Hoeijmakers, Jan H. J., van der Horst, Gijsbertus T. J.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234220/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3234220/

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