Balance between MKK6 and MKK3 Mediates p38 MAPK Associated Resistance to Cisplatin in NSCLC

Balance between MKK6 and MKK3 Mediates p38 MAPK Associated Resistance to Cisplatin in NSCLC

The p38 MAPK signaling pathway has been proposed as a critical mediator of the therapeutic effect of several antitumor agents, including cisplatin. Here, we found that sensitivity to cisplatin, in a system of 7 non-small cell lung carcinoma derived cell lines, correlated with high levels of MKK6 and...

Full description

Bibliographic Details
Main Authors: Galan-Moya, Eva M., de la Cruz-Morcillo, Miguel A., Valero, Maria Llanos, Callejas-Valera, Juan L., Melgar-Rojas, Pedro, Losa, Javier Hernadez, Salcedo, Mayte, Fernández-Aramburo, Antonio, Cajal, Santiago Ramon y., Sánchez-Prieto, Ricardo
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229586/

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3229586/

Similar Items