The IQ Motif is Crucial for Cav1.1 Function
Ca2+-dependent modulation via calmodulin, with consensus CaM-binding IQ motif playing a key role, has been documented for most high-voltage-activated Ca2+ channels. The skeletal muscle Cav1.1 also exhibits Ca2+-/CaM-dependent modulation. Here, whole-cell Ca2+ current, Ca2+ transient, and maximal, im...
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Format: | Online |
Language: | English |
Published: |
Hindawi Publishing Corporation
2011
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3228397/ |