Regulatory T Cells Accumulate in the Lung Allergic Inflammation and Efficiently Suppress T-Cell Proliferation but Not Th2 Cytokine Production

Regulatory T Cells Accumulate in the Lung Allergic Inflammation and Efficiently Suppress T-Cell Proliferation but Not Th2 Cytokine Production

Foxp3+CD25+CD4+ regulatory T cells are vital for peripheral tolerance and control of tissue inflammation. In this study, we characterized the phenotype and monitored the migration and activity of regulatory T cells present in the airways of allergic or tolerant mice after allergen challenge. To indu...

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Bibliographic Details
Main Authors: Faustino, Lucas, Mucida, Daniel, Keller, Alexandre Castro, Demengeot, Jocelyne, Bortoluci, Karina, Sardinha, Luiz Roberto, Carla Takenaka, Maisa, Basso, Alexandre Salgado, Faria, Ana Maria Caetano, Russo, Momtchilo
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2012
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227414/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3227414/

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