Fenfluramine-induced gene dysregulation in human pulmonary artery smooth muscle and endothelial cells

Fenfluramine is prescribed either alone or in combination with phentermine as part of Fen-Phen, an anti-obesity medication. Fenfluramine was withdrawn from the US market in 1997 due to reports of heart valvular disease, pulmonary arterial hypertension, and cardiac fibrosis. Particularly, idiopathic...

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Bibliographic Details
Main Authors: Yao, Weijuan, Mu, Wenbo, Zeifman, Amy, Lofti, Michelle, Remillard, Carmelle V., Makino, Ayako, Perkins, David L., Garcia, Joe G., Yuan, Jason X. J., Zhang, Wei
Format: Online
Language:English
Published: Medknow Publications & Media Pvt Ltd 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3224433/