Direct Lineage Conversions: Unnatural but useful?

Classic experiments such as somatic cell nuclear transfer into oocytes or cell fusion demonstrated that differentiated cells are not irreversibly committed to their fate. More recent work has built on these conclusions and discovered defined factors that directly induce one specific cell type from a...

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Bibliographic Details
Main Authors: Vierbuchen, Thomas, Wernig, Marius
Format: Online
Language:English
Published: 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3222779/