SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE

SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE

We report a 48-year-old immunocompetent male, resident of Central India, who presented with slowly progressive asymptomatic multiple red lesions on different parts of body. On enquiry, the patient gave history of travel to Middle East 6 months back. Examination showed 10 crusted erythematous indurat...

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Main Authors: Madke, Bhushan, Kharkar, Vidya, Chikhalkar, Siddhi, Mahajan, Sunanda, Khopkar, Uday
Format: Online
Language:English
Published: Medknow Publications & Media Pvt Ltd 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221233/
id pubmed-3221233
recordtype oai_dc
spelling pubmed-32212332011-11-25 SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE Madke, Bhushan Kharkar, Vidya Chikhalkar, Siddhi Mahajan, Sunanda Khopkar, Uday Case Report We report a 48-year-old immunocompetent male, resident of Central India, who presented with slowly progressive asymptomatic multiple red lesions on different parts of body. On enquiry, the patient gave history of travel to Middle East 6 months back. Examination showed 10 crusted erythematous indurated plaques and nodules over forearms, left leg, right index finger, left wrist and dorsa of both feet. Histopathological examination of tissue biopsy showed multiple intracellular as well as extracellular leishmania donovan bodies. Keeping in mind the higher rate of side effects to pentavalent antimony, we treated this patient with oral miltefosine 50 mg bid and the lesions showed complete resolution over 4 months of therapy. Medknow Publications & Media Pvt Ltd 2011 /pmc/articles/PMC3221233/ /pubmed/22121288 http://dx.doi.org/10.4103/0019-5154.87165 Text en Copyright: © Indian Journal of Dermatology http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Madke, Bhushan
Kharkar, Vidya
Chikhalkar, Siddhi
Mahajan, Sunanda
Khopkar, Uday
spellingShingle Madke, Bhushan
Kharkar, Vidya
Chikhalkar, Siddhi
Mahajan, Sunanda
Khopkar, Uday
SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE
author_facet Madke, Bhushan
Kharkar, Vidya
Chikhalkar, Siddhi
Mahajan, Sunanda
Khopkar, Uday
author_sort Madke, Bhushan
title SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE
title_short SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE
title_full SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE
title_fullStr SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE
title_full_unstemmed SUCCESSFUL TREATMENT OF MULTIFOCAL CUTANEOUS LEISHMANIASIS WITH MILTEFOSINE
title_sort successful treatment of multifocal cutaneous leishmaniasis with miltefosine
description We report a 48-year-old immunocompetent male, resident of Central India, who presented with slowly progressive asymptomatic multiple red lesions on different parts of body. On enquiry, the patient gave history of travel to Middle East 6 months back. Examination showed 10 crusted erythematous indurated plaques and nodules over forearms, left leg, right index finger, left wrist and dorsa of both feet. Histopathological examination of tissue biopsy showed multiple intracellular as well as extracellular leishmania donovan bodies. Keeping in mind the higher rate of side effects to pentavalent antimony, we treated this patient with oral miltefosine 50 mg bid and the lesions showed complete resolution over 4 months of therapy.
publisher Medknow Publications & Media Pvt Ltd
publishDate 2011
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3221233/
_version_ 1611489245312057344

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