Increased complexity of vasopressin's vascular actions

Vasopressin is becoming a widely used pressor in conditions with severe hypotension. Like several other hormones important in cardiovascular and extracellular fluid control, however, vasopressin can activate several receptors that when pharmacologically or pathologically stimulated may result in con...

Full description

Bibliographic Details
Main Authors: Landry, Donald W, Oliver, Juan A
Format: Online
Language:English
Published: BioMed Central 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220049/
id pubmed-3220049
recordtype oai_dc
spelling pubmed-32200492011-12-13 Increased complexity of vasopressin's vascular actions Landry, Donald W Oliver, Juan A Commentary Vasopressin is becoming a widely used pressor in conditions with severe hypotension. Like several other hormones important in cardiovascular and extracellular fluid control, however, vasopressin can activate several receptors that when pharmacologically or pathologically stimulated may result in conflicting effects. In the present issue of Critical Care, Rehberg and colleagues examined the hypothesis that blockade of vasopressin V2 receptor during septic shock may be beneficial. Their tantalizing results indicate that future work must consider the precise vasopressin receptors that are stimulated and/or inhibited. BioMed Central 2010 2010-12-13 /pmc/articles/PMC3220049/ /pubmed/21156084 http://dx.doi.org/10.1186/cc9344 Text en Copyright ©2010 BioMed Central Ltd
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Landry, Donald W
Oliver, Juan A
spellingShingle Landry, Donald W
Oliver, Juan A
Increased complexity of vasopressin's vascular actions
author_facet Landry, Donald W
Oliver, Juan A
author_sort Landry, Donald W
title Increased complexity of vasopressin's vascular actions
title_short Increased complexity of vasopressin's vascular actions
title_full Increased complexity of vasopressin's vascular actions
title_fullStr Increased complexity of vasopressin's vascular actions
title_full_unstemmed Increased complexity of vasopressin's vascular actions
title_sort increased complexity of vasopressin's vascular actions
description Vasopressin is becoming a widely used pressor in conditions with severe hypotension. Like several other hormones important in cardiovascular and extracellular fluid control, however, vasopressin can activate several receptors that when pharmacologically or pathologically stimulated may result in conflicting effects. In the present issue of Critical Care, Rehberg and colleagues examined the hypothesis that blockade of vasopressin V2 receptor during septic shock may be beneficial. Their tantalizing results indicate that future work must consider the precise vasopressin receptors that are stimulated and/or inhibited.
publisher BioMed Central
publishDate 2010
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3220049/
_version_ 1611488918222405632