Differentiation Syndrome in Promyelocytic Leukemia: Clinical Presentation, Pathogenesis and Treatment

Differentiation syndrome (DS) represents a life-threatening complication in patients with acute promyelocytic leukemia (APL) undergoing induction therapy with all-trans retinoic acid (ATRA) or arsenic trioxide (ATO). It affected about 20–25% of all patients and so far there are no definitive diagnos...

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Bibliographic Details
Main Authors: Rego, E.M., De Santis, G.C.
Format: Online
Language:English
Published: Università Cattolica del Sacro Cuore 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219650/