Castleman's disease in childhood: report of three cases and review of the literature

Castleman's disease (CD) is a rare, localized or generalized, lymphoproliferative disorder with a frequent mediastinal location, but possible in any lymph node or extra nodal site. It usually appears in young adults whilst it rarely occurs in childhood. There are only about 100 pediatric cases...

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Bibliographic Details
Main Authors: Farruggia, Piero, Trizzino, Antonino, Scibetta, Nunzia, Cecchetto, Giovanni, Guerrieri, Patrizia, D'Amore, Emanuele SG, D'Angelo, Paolo
Format: Online
Language:English
Published: BioMed Central 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219574/
Description
Summary:Castleman's disease (CD) is a rare, localized or generalized, lymphoproliferative disorder with a frequent mediastinal location, but possible in any lymph node or extra nodal site. It usually appears in young adults whilst it rarely occurs in childhood. There are only about 100 pediatric cases published, five of them in Italy. We report 3 cases of localized Castleman's disease, investigated in our Department in a 3 years period and reviewed the literature.