βA3/A1-Crystallin controls anoikis-mediated cell death in astrocytes by modulating PI3K/AKT/mTOR and ERK survival pathways through the PKD/Bit1-signaling axis

βA3/A1-Crystallin controls anoikis-mediated cell death in astrocytes by modulating PI3K/AKT/mTOR and ERK survival pathways through the PKD/Bit1-signaling axis

During eye development, apoptosis is vital to the maturation of highly specialized structures such as the lens and retina. Several forms of apoptosis have been described, including anoikis, a form of apoptosis triggered by inadequate or inappropriate cell–matrix contacts. The anoikis regulators, Bit...

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Bibliographic Details
Main Authors: Ma, B, Sen, T, Asnaghi, L, Valapala, M, Yang, F, Hose, S, McLeod, D S, Lu, Y, Eberhart, C, Zigler, J S, Sinha, D
Format: Online
Language:English
Published: Nature Publishing Group 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219085/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3219085/

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