Accelerating drug discovery for Alzheimer's disease: best practices for preclinical animal studies

Animal models have contributed significantly to our understanding of the underlying biological mechanisms of Alzheimer's disease (AD). As a result, over 300 interventions have been investigated and reported to mitigate pathological phenotypes or improve behavior in AD animal models or both. To...

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Bibliographic Details
Main Authors: Shineman, Diana W, Basi, Guriqbal S, Bizon, Jennifer L, Colton, Carol A, Greenberg, Barry D, Hollister, Beth A, Lincecum, John, Leblanc, Gabrielle G, Lee, Linda (Bobbi) H, Luo, Feng, Morgan, Dave, Morse, Iva, Refolo, Lorenzo M, Riddell, David R, Scearce-Levie, Kimberly, Sweeney, Patrick, Yrjänheikki, Juha, Fillit, Howard M
Format: Online
Language:English
Published: BioMed Central 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218805/