Rapid haplotype inference for nuclear families
Hapi is a new dynamic programming algorithm that ignores uninformative states and state transitions in order to efficiently compute minimum-recombinant and maximum likelihood haplotypes. When applied to a dataset containing 103 families, Hapi performs 3.8 and 320 times faster than state-of-the-art a...
| Main Authors: | , , , |
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| Format: | Online |
| Language: | English |
| Published: |
BioMed Central
2010
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218664/ |