The Rotterdam Scan Study: design and update up to 2012

Neuroimaging plays an important role in etiologic research on neurological diseases in the elderly. The Rotterdam Scan Study was initiated as part of the ongoing Rotterdam Study with the aim to unravel causes of neurological disease by performing neuroimaging in a population-based longitudinal setti...

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Main Authors: Ikram, M. Arfan, van der Lugt, Aad, Niessen, Wiro J., Krestin, Gabriel P., Koudstaal, Peter J., Hofman, Albert, Breteler, Monique M. B., Vernooij, Meike W.
Format: Online
Language:English
Published: Springer Netherlands 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218266/
id pubmed-3218266
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spelling pubmed-32182662011-12-09 The Rotterdam Scan Study: design and update up to 2012 Ikram, M. Arfan van der Lugt, Aad Niessen, Wiro J. Krestin, Gabriel P. Koudstaal, Peter J. Hofman, Albert Breteler, Monique M. B. Vernooij, Meike W. Study Update Neuroimaging plays an important role in etiologic research on neurological diseases in the elderly. The Rotterdam Scan Study was initiated as part of the ongoing Rotterdam Study with the aim to unravel causes of neurological disease by performing neuroimaging in a population-based longitudinal setting. In 1995 and 1999 random subsets of the Rotterdam Study underwent neuroimaging, whereas from 2005 onwards MRI has been implemented into the core protocol of the Rotterdam Study. In this paper, we discuss the background and rationale of the Rotterdam Scan Study. We also describe the imaging protocol and post-processing techniques, and highlight the main findings to date. Finally, we make recommendations for future research, which will also be the main focus of investigation in the Rotterdam Scan Study. Springer Netherlands 2011-10-16 2011-10 /pmc/articles/PMC3218266/ /pubmed/22002080 http://dx.doi.org/10.1007/s10654-011-9624-z Text en © The Author(s) 2011
repository_type Open Access Journal
institution_category Foreign Institution
institution US National Center for Biotechnology Information
building NCBI PubMed
collection Online Access
language English
format Online
author Ikram, M. Arfan
van der Lugt, Aad
Niessen, Wiro J.
Krestin, Gabriel P.
Koudstaal, Peter J.
Hofman, Albert
Breteler, Monique M. B.
Vernooij, Meike W.
spellingShingle Ikram, M. Arfan
van der Lugt, Aad
Niessen, Wiro J.
Krestin, Gabriel P.
Koudstaal, Peter J.
Hofman, Albert
Breteler, Monique M. B.
Vernooij, Meike W.
The Rotterdam Scan Study: design and update up to 2012
author_facet Ikram, M. Arfan
van der Lugt, Aad
Niessen, Wiro J.
Krestin, Gabriel P.
Koudstaal, Peter J.
Hofman, Albert
Breteler, Monique M. B.
Vernooij, Meike W.
author_sort Ikram, M. Arfan
title The Rotterdam Scan Study: design and update up to 2012
title_short The Rotterdam Scan Study: design and update up to 2012
title_full The Rotterdam Scan Study: design and update up to 2012
title_fullStr The Rotterdam Scan Study: design and update up to 2012
title_full_unstemmed The Rotterdam Scan Study: design and update up to 2012
title_sort rotterdam scan study: design and update up to 2012
description Neuroimaging plays an important role in etiologic research on neurological diseases in the elderly. The Rotterdam Scan Study was initiated as part of the ongoing Rotterdam Study with the aim to unravel causes of neurological disease by performing neuroimaging in a population-based longitudinal setting. In 1995 and 1999 random subsets of the Rotterdam Study underwent neuroimaging, whereas from 2005 onwards MRI has been implemented into the core protocol of the Rotterdam Study. In this paper, we discuss the background and rationale of the Rotterdam Scan Study. We also describe the imaging protocol and post-processing techniques, and highlight the main findings to date. Finally, we make recommendations for future research, which will also be the main focus of investigation in the Rotterdam Scan Study.
publisher Springer Netherlands
publishDate 2011
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3218266/
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