Characterisation of a C1qtnf5 Ser163Arg Knock-In Mouse Model of Late-Onset Retinal Macular Degeneration

Characterisation of a C1qtnf5 Ser163Arg Knock-In Mouse Model of Late-Onset Retinal Macular Degeneration

A single founder mutation resulting in a Ser163Arg substitution in the C1QTNF5 gene product causes autosomal dominant late-onset retinal macular degeneration (L-ORMD) in humans, which has clinical and pathological features resembling age-related macular degeneration. We generated and characterised a...

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Bibliographic Details
Main Authors: Shu, Xinhua, Luhmann, Ulrich F. O., Aleman, Tomas S., Barker, Susan E., Lennon, Alan, Tulloch, Brian, Chen, Mei, Xu, Heping, Jacobson, Samuel G., Ali, Robin, Wright, Alan F.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217991/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217991/

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