Integrated genomic approaches to identification of candidate genes underlying metabolic and cardiovascular phenotypes in the spontaneously hypertensive rat

The spontaneously hypertensive rat (SHR) is a widely used rodent model of hypertension and metabolic syndrome. Previously we identified thousands of cis-regulated expression quantitative trait loci (eQTLs) across multiple tissues using a panel of rat recombinant inbred (RI) strains derived from Brow...

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Bibliographic Details
Main Authors: Morrissey, Catherine, Grieve, Ian C., Heinig, Matthias, Atanur, Santosh, Petretto, Enrico, Pravenec, Michal, Hubner, Norbert, Aitman, Timothy J.
Format: Online
Language:English
Published: American Physiological Society 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3217321/