The endocytic protein GRAF1 is directed to cell-matrix adhesion sites and regulates cell spreading

GTPase regulator associated with focal adhesion kinase-1 (GRAF1) interacted with endocytic and adhesion proteins, and GRAF1 endocytic activity was up-regulated in spreading cells and concentrated at the leading edge of migrating cells. Depletion of GRAF1 resulted in profound defects in cell spreadin...

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Bibliographic Details
Main Authors: Doherty, Gary J., Åhlund, Monika K., Howes, Mark T., Morén, Björn, Parton, Robert G., McMahon, Harvey T., Lundmark, Richard
Format: Online
Language:English
Published: The American Society for Cell Biology 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3216663/