Methyl 2-{[(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene)(thiophen-2-yl)methyl]amino}-3-phenylpropionate

Methyl 2-{[(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene)(thiophen-2-yl)methyl]amino}-3-phenylpropionate

In the title compound, C25H23N3O3S, an intramolecular N—H⋯O interaction generates an S(6) ring, which stabilizes the enamine–keto form of the compound. This S(6) ring and the pyrazole ring are essentially coplanar, making a dihedral angle of 1.49 (6)°. The bond lengths within the S(6) ring of the...

Full description

Bibliographic Details
Main Authors:	Zhu, Hualing, Zhao, Xinxin, Wang, Zhan, Ren, Junjie, Zhang, Miao
Format:	Online
Language:	English
Published:	International Union of Crystallography 2011
Online Access:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3213630/

Similar Items

1,5-Dimethyl-4-{[(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene)(thiophen-2-yl)methyl]amino}-2-phenyl-1H-pyrazol-3(2H)-one
by: Zhu, Hualing, et al.
Published: (2011)

Methyl 2-{[(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene)(4-nitrophenyl)methyl]amino}-3-phenylpropanoate
by: Zhang, Xin, et al.
Published: (2012)

Methyl 2-{[(2-furyl)(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene)methyl]amino}acetate
by: Han, Xiao, et al.
Published: (2011)

N′-[(5-Methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)(thiophen-2-yl)methylidene]benzohydrazide
by: Zhu, Hualing, et al.
Published: (2012)

1-(4-Methylphenyl)-3-phenyl-1H-pyrazol-5-yl 4-nitrobenzenesulfonate
by: Wardell, Solange M. S. V., et al.
Published: (2012)

3-Methyl-4-{[(3-{[(3-methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene)(phenyl)methyl]aminomethyl}benzyl)amino](phenyl)methylidene}-1-phenyl-1H-pyrazol-5(4H)-one
by: Cai, Hong-Xin, et al.
Published: (2011)

1-(4-Methylphenylsulfonyl)-5-phenyl-4,5-dihydro-1H-pyrazole
by: Li, Jie, et al.
Published: (2011)

1-(4-{[(1,3,3-Trimethylindolin-2-ylidene)methyl]diazenyl}phenyl)ethanone
by: Gainsford, Graeme J., et al.
Published: (2013)

3-Methyl-1-phenyl-4-[(Z)-phenyl(4-acetamidoanilino)methylidene]-1H-pyrazol-5(4H)-one
by: Zhi, Li-Hua, et al.
Published: (2012)

3-Methyl-1-phenyl-4-[(phenyl)(2-phenylhydrazin-1-yl)methylidene]-1H-pyrazol-5(4H)-one
by: Idemudia, Omoruyi G., et al.
Published: (2012)

Ethyl 1-(4-methylphenyl)-5-phenyl-4-phenylsulfonyl-1H-pyrazole-3-carboxylate
by: Abdel-Aziz, Hatem A., et al.
Published: (2011)

3,5-Bis(4-methylphenyl)-1-phenyl-4,5-dihydro-1H-pyrazole
by: Butcher, Ray J., et al.
Published: (2011)

1-[1-(3-Methylphenyl)-5-phenyl-4-phenylsulfonyl-1H-pyrazol-3-yl]ethanone
by: Ghazzali, Mohamed, et al.
Published: (2011)

(Z)-4-[(2-Aminoanilino)(phenyl)methylidene]-3-methyl-1-phenyl-1H-pyrazol-5(4H)-one
by: Lu, Rong, et al.
Published: (2011)

Crystal structure of 4-[(2,4-dichlorophenyl)(5-hydroxy-3-methyl-1-phenyl-1H-pyrazol-4-yl)methyl]-5-methyl-2-phenyl-2,3-dihydro-1H-pyrazol-3-one
by: Kumar, Balbir, et al.
Published: (2015)

(5-Hydroxy-3-methyl-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)(pyridin-4-yl)methanone monohydrate
by: Kargar, Hadi, et al.
Published: (2010)

4-{[2-(2,4-Dinitrophenyl)hydrazinylidene](phenyl)methyl}-5-methyl-2-phenyl-1H-pyrazol-3(2H)-one ethanol monosolvate
by: Idemudia, Omoruyi G., et al.
Published: (2012)

2-{[(4-{[(2-Hydroxyphenyl)(phenyl)methylidene]amino}phenyl)imino](phenyl)methyl}phenol
by: Blagus, Anita, et al.
Published: (2011)

Crystal structure of 3-(4-methylphenyl)-1-phenyl-5-[(E)-2-phenylethenyl]-1H-pyrazole
by: Adam, Farook, et al.
Published: (2015)

(R)-[(R)-3-Benzyl-2-oxooxazolidin-4-yl][4-(methylsulfonyl)phenyl]methyl acetate
by: Li, Feng, et al.
Published: (2014)

(E)-3-Methyl-5-(4-methylphenoxy)-1-phenyl-1H-pyrazole-4-carbaldehyde O-[(2-chloro-1,3-thiazol-5-yl)methyl]oxime
by: Dai, Hong, et al.
Published: (2011)

N-(4-Acetyl-3-methyl-1-phenyl-1H-pyrazol-5-yl)-N-methyl-2-(2-methyl-4-oxo-3,4-dihydroquinazolin-3-yl)benzamide
by: Meneghetti, Fiorella, et al.
Published: (2013)

N-(4-Aminopyrimidin-5-yl)-4-methyl-N-(4-methylphenylsulfonyl)benzenesulfonamide
by: Taher, Abu, et al.
Published: (2012)

4-(4-Chlorobenzyl)-5-methyl-2-phenyl-1H-pyrazol-3(2H)-one
by: Mohamed, Shaaban K., et al.
Published: (2011)

(4-Hydroxy-3-methylphenyl)(phenyl)methanone
by: Dileep, C. S., et al.
Published: (2013)

[1-(4-Chlorophenyl)-5-hydroxy-3-phenyl-1H-pyrazol-4-yl](thiophen-2-yl)methanone
by: Deng, Gui-Ming, et al.
Published: (2012)

3-Acetyl-1-(3-methylphenyl)-5-phenyl-1H-pyrazole-4-carbonitrile
by: Abdel-Aziz, Hatem A., et al.
Published: (2012)

(Furan-2-yl)(5-hydroxy-3-methyl-5-phenyl-4,5-dihydro-1H-pyrazol-1-yl)methanone
by: Kargar, Hadi, et al.
Published: (2011)

(Z)-4-[(3-Aminonaphthalen-2-ylamino)(phenyl)methylidene]-3-methyl-1-phenyl-1H-pyrazol-5(4H)-one
by: Zhang, Zhao, et al.
Published: (2012)

2-[(E)-Phenyl(2-phenylhydrazin-1-ylidene)methyl]phenol
by: Howie, R. Alan, et al.
Published: (2012)

5-Methyl-1-[(4-methylphenyl)sulfonyl]-1H-pyrazol-3-yl 4-methylbenzenesulfonate
by: Murtaza, Shahzad, et al.
Published: (2012)

3-[5-Methyl-1-(4-methylphenyl)-1H-1,2,3-triazol-4-yl]-N-phenyl-5-[4-(piperidin-1-yl)phenyl]-4,5-dihydro-1H-pyrazole-1-carbothioamide dimethylformamide hemisolvate
by: Abdel-Wahab, Bakr F., et al.
Published: (2012)

(4-Methylphenyl)[2-(thiophen-2-ylcarbonyl)phenyl]methanone
by: Silambarasan, V., et al.
Published: (2011)

4-(4-Chlorobenzoyl)-3-methyl-1-phenyl-1H-pyrazol-5-yl 4-chlorobenzoate
by: Li, Xiao-Xia, et al.
Published: (2011)

5-[(3,5-Dichloroanilino)methyl]-N-(3,5-dichlorophenyl)-6-methyl-2-phenylpyrimidin-4-amine
by: Cieplik, Jerzy, et al.
Published: (2012)

4-Methyl-N-{4-[(5-methyl-1,2-oxazol-3-yl)sulfamoyl]phenyl}benzenesulfonamide
by: Sohail, Muhammad, et al.
Published: (2012)

Methyl 2-[(3RS,4RS)-3-phenyl-4-(phenylsulfonyl)isoxazolidin-2-yl]acetate
by: Gültekin, Zeynep, et al.
Published: (2014)

2-[1-({2-[1-(2-Hydroxy-5-{[methyl(phenyl)amino]methyl}phenyl)ethylideneamino]ethyl}imino)ethyl]-4-{[methyl(phenyl)amino]methyl}phenol
by: Ourari, Ali, et al.
Published: (2012)

N′-[(4Z)-1-(3-Methyl-5-oxo-1-phenyl-4,5-dihydro-1H-pyrazol-4-ylidene)hexyl]benzenesulfonohydrazide
by: Ukwueze, Nkechinyere N., et al.
Published: (2014)

4-[5-(4-Fluorophenyl)-1-(4-phenyl-1,3-thiazol-2-yl)-4,5-dihydro-1H-pyrazol-3-yl]-5-methyl-1-(4-methylphenyl)-1H-1,2,3-triazole
by: Abdel-Wahab, Bakr F., et al.
Published: (2013)