Thrombin A-Chain: Activation Remnant or Allosteric Effector?

Although prothrombin is one of the most widely studied enzymes in biology, the role of the thrombin A-chain has been neglected in comparison to the other domains. This paper summarizes the current data on the prothrombin catalytic domain A-chain region and the subsequent thrombin A-chain. Attention...

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Bibliographic Details
Main Authors: Carter, Isis S. R., Vanden Hoek, Amanda L., Pryzdial, Edward L. G., MacGillivray, Ross T. A.
Format: Online
Language:English
Published: Hindawi Publishing Corporation 2010
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3211113/