Regulation of the HIV-1 promoter by HIF-1α and Vpr proteins
We previously demonstrated the ability of HIV-1 Vpr protein to activate the oxidative stress pathway, thus leading to the induction of the hypoxia inducible factor 1 alpha (HIF-1α). Therefore, we sought to examine the interplay between the two proteins and the impact of HIF-1α activation on HIV-1 tr...
| Main Authors: | , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
BioMed Central
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3210103/ |