Upregulation of Cardiomyocyte Ribonucleotide Reductase Increases Intracellular 2 deoxy-ATP, Contractility, and Relaxation
We have previously demonstrated that substitution of ATP with 2 deoxy-ATP (dATP) increased the magnitude and rate of force production at all levels of Ca2+-mediated activation in demembranated cardiac muscle. In the current study we hypothesized that cellular [dATP] could be increased by viral-media...
| Main Authors: | , , , , , , , |
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| Format: | Online |
| Language: | English |
| Published: |
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3208740/ |