Epithelial Mesenchymal Transition by C-Fos Estrogen Receptor Activation Involves Nuclear Translocation of β-Catenin and Upregulation of β-Catenin/Lymphoid Enhancer Binding Factor-1 Transcriptional Activity

Mouse mammary epithelial cells expressing a fusion protein of c-Fos and the estrogen receptor (FosER) formed highly polarized epithelial cell sheets in the absence of estradiol. β-Catenin and p120ctn were exclusively located at the lateral plasma membrane in a tight complex with the adherens junctio...

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Bibliographic Details
Main Authors: Eger, Andreas, Stockinger, Andreas, Schaffhauser, Birgit, Beug, Hartmut, Foisner, Roland
Format: Online
Language:English
Published: The Rockefeller University Press 2000
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3207144/