Methylation of the CpG Sites Only on the Sense Strand of the APC Gene Is Specific for Hepatocellular Carcinoma

Hypermethylation of the promoter of the tumor suppressor gene, adenomatous polyposis coli (APC), occurs in various malignancies, including hepatocellular carcinoma (HCC). However, reports on the specificity of the methylation of the APC gene for HCC have varied. To gain insight into how these variat...

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Bibliographic Details
Main Authors: Jain, Surbhi, Chang, Ting-Tsung, Hamilton, James P., Lin, Selena Y., Lin, Yih-Jyh, Evans, Alison A., Selaru, Florin M., Lin, Pin- Wen, Chen, Shun-Hua, Block, Timothy M., Hu, Chi-Tan, Song, Wei, Meltzer, Stephen J., Su, Ying-Hsiu
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206845/