A Novel Dimer-Tetramer Transition Captured by the Crystal Structure of the HIV-1 Nef

A Novel Dimer-Tetramer Transition Captured by the Crystal Structure of the HIV-1 Nef

HIV-1 Nef modulates disease progression through interactions with over 30 host proteins. Individual chains fold into membrane-interacting N-terminal and C-terminal core (Nefcore) domains respectively. Nef exists as small oligomers near membranes and associates into higher oligomers such as tetramers...

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Bibliographic Details
Main Authors: Singh, Pankaj, Yadav, Gaya Prasad, Gupta, Sudeepti, Tripathi, Anil Kumar, Ramachandran, Ravishankar, Tripathi, Raj Kamal
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206816/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206816/

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