Roles for α2P24 and Copi in Endoplasmic Reticulum Cargo Exit Site Formation

A two-step reconstitution system for the generation of ER cargo exit sites from starting ER-derived low density microsomes (LDMs; 1.17 g/cc) is described. The first step is mediated by the hydrolysis of Mg2+ATP and Mg2+GTP, leading to the formation of a transitional ER (tER) with the soluble cargo a...

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Bibliographic Details
Main Authors: Lavoie, C., Paiement, J., Dominguez, M., Roy, L., Dahan, S., Gushue, J.N., Bergeron, J.J.M.
Format: Online
Language:English
Published: The Rockefeller University Press 1999
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206572/