Unique Interplay between Sugar and Lipid in Determining the Antigenic Potency of Bacterial Antigens for NKT Cells

Structural and biophysical studies reveal the induced-fit mechanism underlying the stringent specificity of invariant natural killer T cells for unique glycolipid antigens from the pathogen Streptococcus pneumoniae.

Bibliographic Details
Main Authors: Girardi, Enrico, Yu, Esther Dawen, Li, Yali, Tarumoto, Norihito, Pei, Bo, Wang, Jing, Illarionov, Petr, Kinjo, Yuki, Kronenberg, Mitchell, Zajonc, Dirk M.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3206013/