Are there differences in acute phase inflammation markers regarding the type of heart failure?
This study aimed to determine if there are differences in inflammatory markers in the acute phase between systolic heart failure and heart failure with preserved systolic function. One hundred and thirty-one patients with acute heart failure were recruited consecutively. At admission, plasma fibrino...
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| Format: | Online |
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PAGEPress Publications
2011
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| Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205787/ |
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pubmed-32057872011-11-02 Are there differences in acute phase inflammation markers regarding the type of heart failure? Sánchez-Lázaro, Ignacio J. Almenar-Bonet, Luis Reganon-Salvador, Edelmiro Vila-Liante, Virtudes Martínez-Sales, Vicenta Martínez-Dolz, Luis Agüero-Ramón-Llin, Jaime Salvador-Sanz, Antonio Clinical Investigation This study aimed to determine if there are differences in inflammatory markers in the acute phase between systolic heart failure and heart failure with preserved systolic function. One hundred and thirty-one patients with acute heart failure were recruited consecutively. At admission, plasma fibrinogen, C-reactive protein, sialic acid, von Willebrand factor, vascular endothelial growth factor, interleukin-6 and NTproBNP were all evaluated. If the ejection fraction was 45% or over patients were included in the HF-PSF group; the remaining patients were included in the SHF group. The HF-PSF patients were older (72±10 vs 63±12 years, P<0.001), presented a higher rate of atrial fibrillation (56.1 vs 21.3%, P<0.001), and had a lower rate of hemoglobin (12.2±2 vs 13.3±2.1 g/dL, P<0.01). No significant differences were observed in the inflammation markers analyzed among SHF and HF-PSF groups. In the acute phase of heart failure there is a marked elevation of inflammatory markers but there are no differences in the inflammatory markers analyzed between the two different types of heart failure. PAGEPress Publications 2011-10-20 /pmc/articles/PMC3205787/ /pubmed/22049314 http://dx.doi.org/10.4081/hi.2011.e17 Text en ©Copyright I.J. Sánchez-Lázaro et al., 2011 This work is licensed under a Creative Commons Attribution NonCommercial 3.0 License (CC BY-NC 3.0). Licensee PAGEPress, Italy |
| repository_type |
Open Access Journal |
| institution_category |
Foreign Institution |
| institution |
US National Center for Biotechnology Information |
| building |
NCBI PubMed |
| collection |
Online Access |
| language |
English |
| format |
Online |
| author |
Sánchez-Lázaro, Ignacio J. Almenar-Bonet, Luis Reganon-Salvador, Edelmiro Vila-Liante, Virtudes Martínez-Sales, Vicenta Martínez-Dolz, Luis Agüero-Ramón-Llin, Jaime Salvador-Sanz, Antonio |
| spellingShingle |
Sánchez-Lázaro, Ignacio J. Almenar-Bonet, Luis Reganon-Salvador, Edelmiro Vila-Liante, Virtudes Martínez-Sales, Vicenta Martínez-Dolz, Luis Agüero-Ramón-Llin, Jaime Salvador-Sanz, Antonio Are there differences in acute phase inflammation markers regarding the type of heart failure? |
| author_facet |
Sánchez-Lázaro, Ignacio J. Almenar-Bonet, Luis Reganon-Salvador, Edelmiro Vila-Liante, Virtudes Martínez-Sales, Vicenta Martínez-Dolz, Luis Agüero-Ramón-Llin, Jaime Salvador-Sanz, Antonio |
| author_sort |
Sánchez-Lázaro, Ignacio J. |
| title |
Are there differences in acute phase inflammation markers regarding the type of heart failure? |
| title_short |
Are there differences in acute phase inflammation markers regarding the type of heart failure? |
| title_full |
Are there differences in acute phase inflammation markers regarding the type of heart failure? |
| title_fullStr |
Are there differences in acute phase inflammation markers regarding the type of heart failure? |
| title_full_unstemmed |
Are there differences in acute phase inflammation markers regarding the type of heart failure? |
| title_sort |
are there differences in acute phase inflammation markers regarding the type of heart failure? |
| description |
This study aimed to determine if there are differences in inflammatory markers in the acute phase between systolic heart failure and heart failure with preserved systolic function. One hundred and thirty-one patients with acute heart failure were recruited consecutively. At admission, plasma fibrinogen, C-reactive protein, sialic acid, von Willebrand factor, vascular endothelial growth factor, interleukin-6 and NTproBNP were all evaluated. If the ejection fraction was 45% or over patients were included in the HF-PSF group; the remaining patients were included in the SHF group. The HF-PSF patients were older (72±10 vs 63±12 years, P<0.001), presented a higher rate of atrial fibrillation (56.1 vs 21.3%, P<0.001), and had a lower rate of hemoglobin (12.2±2 vs 13.3±2.1 g/dL, P<0.01). No significant differences were observed in the inflammation markers analyzed among SHF and HF-PSF groups. In the acute phase of heart failure there is a marked elevation of inflammatory markers but there are no differences in the inflammatory markers analyzed between the two different types of heart failure. |
| publisher |
PAGEPress Publications |
| publishDate |
2011 |
| url |
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205787/ |
| _version_ |
1611484905548546048 |