CCL28 Induces Mucosal Homing of HIV-1-Specific IgA-Secreting Plasma Cells in Mice Immunized with HIV-1 Virus-Like Particles

CCL28 Induces Mucosal Homing of HIV-1-Specific IgA-Secreting Plasma Cells in Mice Immunized with HIV-1 Virus-Like Particles

Mucosae-associated epithelial chemokine (MEC or CCL28) binds to CCR3 and CCR10 and recruits IgA-secreting plasma cells (IgA-ASCs) in the mucosal lamina propria. The ability of this chemokine to enhance migration of IgA-ASCs to mucosal sites was assessed in a mouse immunization model using HIV-1IIIB...

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Bibliographic Details
Main Authors: Rainone, Veronica, Dubois, Gregor, Temchura, Vladimir, Überla, Klaus, Clivio, Alberto, Nebuloni, Manuela, Lauri, Eleonora, Trabattoni, Daria, Veas, Francisco, Clerici, Mario
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205026/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3205026/

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