A pharmacological cocktail for arresting actin dynamics in living cells

In this paper, we report a new combination of actin inhibitors optimized to rapidly arrest actin dynamics while preserving the actin network. Using this drug combination, we demonstrate that actin dynamics, but not actin structure, are required for the spatial persistence of Rac activation in HL-60...

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Bibliographic Details
Main Authors: Peng, Grace E., Wilson, Sarah R., Weiner, Orion D.
Format: Online
Language:English
Published: The American Society for Cell Biology 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3204061/