Leishmania Mitochondrial Peroxiredoxin Plays a Crucial Peroxidase-Unrelated Role during Infection: Insight into Its Novel Chaperone Activity

Two-cysteine peroxiredoxins are ubiquitous peroxidases that play various functions in cells. In Leishmania and related trypanosomatids, which lack catalase and selenium-glutathione peroxidases, the discovery of this family of enzymes provided the molecular basis for peroxide removal in these organis...

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Bibliographic Details
Main Authors: Castro, Helena, Teixeira, Filipa, Romao, Susana, Santos, Mariana, Cruz, Tânia, Flórido, Manuela, Appelberg, Rui, Oliveira, Pedro, Ferreira-da-Silva, Frederico, Tomás, Ana M.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3203189/