Clostridium perfringens Iota-Toxin: Structure and Function
Clostridium perfringens iota-toxin is composed of the enzyme component (Ia) and the binding component (Ib). Ib binds to receptor on targeted cells and translocates Ia into the cytosol of the cells. Ia ADP-ribosylates actin, resulting in cell rounding and death. Comparisons of the deduced amino acid...
Main Authors: | , , , , |
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Format: | Online |
Language: | English |
Published: |
Molecular Diversity Preservation International
2009
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Online Access: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202787/ |