Clostridium perfringens Iota-Toxin: Structure and Function

Clostridium perfringens iota-toxin is composed of the enzyme component (Ia) and the binding component (Ib). Ib binds to receptor on targeted cells and translocates Ia into the cytosol of the cells. Ia ADP-ribosylates actin, resulting in cell rounding and death. Comparisons of the deduced amino acid...

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Bibliographic Details
Main Authors: Sakurai, Jun, Nagahama, Masahiro, Oda, Masataka, Tsuge, Hideaki, Kobayashi, Keiko
Format: Online
Language:English
Published: Molecular Diversity Preservation International 2009
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202787/