A Novel Metagenomic Short-Chain Dehydrogenase/Reductase Attenuates Pseudomonas aeruginosa Biofilm Formation and Virulence on Caenorhabditis elegans

A Novel Metagenomic Short-Chain Dehydrogenase/Reductase Attenuates Pseudomonas aeruginosa Biofilm Formation and Virulence on Caenorhabditis elegans

In Pseudomonas aeruginosa, the expression of a number of virulence factors, as well as biofilm formation, are controlled by quorum sensing (QS). N-Acylhomoserine lactones (AHLs) are an important class of signaling molecules involved in bacterial QS and in many pathogenic bacteria infection and host...

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Bibliographic Details
Main Authors: Bijtenhoorn, Patrick, Mayerhofer, Hubert, Müller-Dieckmann, Jochen, Utpatel, Christian, Schipper, Christina, Hornung, Claudia, Szesny, Matthias, Grond, Stephanie, Thürmer, Andrea, Brzuszkiewicz, Elzbieta, Daniel, Rolf, Dierking, Katja, Schulenburg, Hinrich, Streit, Wolfgang R.
Format: Online
Language:English
Published: Public Library of Science 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202535/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3202535/

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