Efficiently identifying genome-wide changes with next-generation sequencing data

We propose a new and effective statistical framework for identifying genome-wide differential changes in epigenetic marks with ChIP-seq data or gene expression with mRNA-seq data, and we develop a new software tool EpiCenter that can efficiently perform data analysis. The key features of our framewo...

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Bibliographic Details
Main Authors: Huang, Weichun, Umbach, David M., Vincent Jordan, Nicole, Abell, Amy N., Johnson, Gary L., Li, Leping
Format: Online
Language:English
Published: Oxford University Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201882/