Chk2-dependent HuR phosphorylation regulates occludin mRNA translation and epithelial barrier function

Chk2-dependent HuR phosphorylation regulates occludin mRNA translation and epithelial barrier function

Occludin is a transmembrane tight junction (TJ) protein that plays an important role in TJ assembly and regulation of the epithelial barrier function, but the mechanisms underlying its post-transcriptional regulation are unknown. The RNA-binding protein HuR modulates the stability and translation of...

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Bibliographic Details
Main Authors: Yu, Ting-Xi, Wang, Peng-Yuan, Rao, Jaladanki N., Zou, Tongtong, Liu, Lan, Xiao, Lan, Gorospe, Myriam, Wang, Jian-Ying
Format: Online
Language:English
Published: Oxford University Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201881/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201881/

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