Sequence determinants for the tandem recognition of UGU and CUG rich RNA elements by the two N—terminal RRMs of CELF1

Sequence determinants for the tandem recognition of UGU and CUG rich RNA elements by the two N—terminal RRMs of CELF1

CUGBP, Elav-like family member 1 (CELF1) is an RNA binding protein with important roles in the regulation of splicing, mRNA decay and translation. CELF1 contains three RNA recognition motifs (RRMs). We used gel retardation, gel filtration, isothermal titration calorimetry and NMR titration studies t...

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Bibliographic Details
Main Authors: Edwards, John, Malaurie, Emilie, Kondrashov, Alexander, Long, Jed, de Moor, Cornelia H., Searle, Mark S., Emsley, Jonas
Format: Online
Language:English
Published: Oxford University Press 2011
Online Access:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201864/

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3201864/

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